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99% Mometasone Furoate Powder CAS 83919-23-7

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Details

 Mometasone furoate
CAS No: 83919-23-7
MF: C27H30CI2O6
MW: 521.43
EINECS: 617-501-0
Purity: 99%
Application: Pharmaceutical intermediate
Appearance: White Powder
Capacity: 500kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years


Function

This product is a white or cream-like cream of emulsion type. Each gram of Aloesone cream contains 0.1% mometasone furoate. Other inactive ingredients are white petrolatum, white wax, propylene glycol ethylene glycol stearate, titanium dioxide, water and phosphoric acid solution.
Pharmacology and Toxicology This product is a synthetic glucocorticoid, which has anti-inflammatory and anti-allergic effects. It is characterized by an increase in the strength of action and a disproportionate increase in side effects, and it is only used once a day.
[Indications] Skin inflammations and pruritus caused by skin diseases that are effective in corticosteroid treatment, such as neurodermatitis, eczema, atopic dermatitis, seborrheic dermatitis, and psoriasis.


COA

Items

Standard

Results

Description  

White to off-white   powder

Off-white  powder

Solubility

Soluble in acetone and in methylene chloride.

complies

Identification  

A: Infrared  Absorption

complies

B:HPLC

complies

Melting point

About 220

221.5222.5

Specific rotation  

+56.0°~+62.0°   

+60.1°

Loss on drying  

max.0.5%   

0.27%

Water

max.0.5%  

0.24%

Residue on ignition      

max.0.1%  

0.03%

Heavy metals          

max.30ppm    

complies

Chromatographic purity (TLC)  

-single impurity        

max. 1.0%

complies

- total impurities        

max. 2.0%

complies

Assay

(HPLC, based on drying)

97.0%102.0%   

99.5%

Residual Solvent

Methanol

not more than 3000ppm

complies

Ethyl acetate

not more than 5000ppm

complies

Acetone

not more than 5000ppm

complies

Pyridine

not more than 200ppm

complies

Methylene chloride

not more than 600ppm

complies

Chloroform

not more than 60ppm

complies

Particle size

90%10um 100%20um

complies

Conclusion: The product complies with the requirements of USP39 Standard.

Analyst

panyong

Checker

panwang

Approved by

yangmingcheng