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Veterinary Parasite resistance Ivermectin 98% CAS: 70288-86-7 / Ivermectin

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 Ivermectin powder


Ivermectin: Ivomec; Heartgard-30

Molecular Structure: 

Molecular Formula: C48H74O14

Molecular Weight: 875.11

CAS No.: 70288-86-7

EINECS: 274-536-0

FeaturesBroad –spectrum resistance effect, safe application to varieties of animals.

;Promote growth ;   Anti-stress agent, reduce body stress during the insecticidal process.

Dosage: Mixed feed, cattle, sheep. Pigs and poultry 0.1-0.15g per 1kg body weight, or 30-50 kg the feed added to the drug 50g. Dogs, cats and rabbits 0.2g per body weight, or every30kg the feed added to the drug 50g, 10 days a repeat when killing parasites.

Storage:Keep Dry and Keep away from Sunlight

Standard: EP/USP

Packing: 25kg/drum

Shelf Time:2 year

Purity:99%
Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.

Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.

Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorine ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.


Ivermectin Analysis


Function

1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to oral semisynthetic broad-spectrum drug resistant parasites. 
2. Ivermectin has effect for most of the various life cycle nematodes. 
3. Ivermectin has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus 
4. Ivermectin has effect for dung round worms that is only stay in intestinal tract 
5. Ivermectin has selective inhibition. 
6. Ivermectin can not go through the blood brain barrier of humanbeings


Application


In veterinary medicine ivermectin is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic in over-dosage.

It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein); affected animals are particularly sensitive to the toxic effects of ivermectin.

Clinical evidence suggests kittens are susceptible to ivermectin toxicity. A 0.01% ivermectin topical preparation for treating ear mites in cats (Acarexx) is available.

Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly contraindicated.


Packing & Storage


Pack in paper-drums and two plastic-bags inside. Net Weight: 25kgs/paper-drum.
1kg-5kgs plastic bag inside with aluminum foil bag outside. Net Weight: 20kgs-25kgs/paper-drum.
Store in a well-closed container away from moisture and light.


Shelf Life

2 years if sealed and store away from direct sun light.


Ivermectin tablets 


Composition: Ivermectin

Specification:150mg,250mg,300mg,600mg or according to customer requirements.

Application: Cattle, Fowl, Pets, Pig 

Packaging Detail: 
(1)10tablets/bsliter, 10blisters/carton; 
(2)60tablets/bottle
(3)Specified by customer requirements. 
Place of Origin: Hebei(China)

INDICATIONS:

For the prevention and treatment of gastrointestinal nematodes of livestock, leather fly maggots, fly larvae grain leather, sheep nasal bot,

itch mites, sheep and pig scabies and other parasitic insects, disease.

Precautions 
1 Long-term continuous use can cause drug resistance and crossed drug resistance. 
2 Do not use during pregnancy. Especially for the first 45 days of pregnancy.

Withdrawal period
cattle 14 days, sheep and goats 4 days, 60 hours after weaning.

Storage: Store in a cool and dark place,protect from light

Dosage:As directed by the veterinarian