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Terbinafine hydrochloride CAS No.78628-80-5 Pharmaceutical


Terbinafine hydrochloride CAS No.78628-80-5 Pharmaceutical Ingredient

Terbinafine Hydrochloride 

1.Standard: EP 

2.Purity: 99% 

3.Packing: 25kgs/drum 

4.Function: antifungal

5.Molecular Formula:C21H25N.HCl;C21H26ClN

6.Molecular Weight:327.90 

7.CAS Number:78628-80-5

8. package: 1kg/bag, 25kg/drum

9. MOQ: 1kg

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.

Terbinafine Hydrochloride Analysis


1.Terbinafine Hcl is mainly effective on the dermatophyte group of fungi.

2.As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.

3.Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied.

4.Terbinafine hydrochloride may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.